General and Organic Chemistry, 20 credits

Upon completion of the course, the student should be able to:
regarding knowledge and understanding:

• describe, classify and systematically name (organic) molecules based on chemical and physical characteristics,
• explain and predict mechanisms of basic organic-chemical reactions,
• describe and classify chemicals according to their risks in the laboratory and for the environment,
• describe the relationships between molecular structure and pharmacological effect of drugs and between their physico-chemical properties and bioavailability.

Regarding skills and abilities:
 

• perform basic organic-chemical laboratory work independently and safely, have knowledge of and be able to describe the risks associated with the procedures and chemicals used,
• describe and analyse own organic-chemical laboratory work by, for example, writing a well-structured, understandable and complete report following scientific ethics for publishing results,
• choose separation and analytical methods for basic chemical problems and interpret simple chromatograms and analysis spectra,
• search and find relevant original and overview literature concerning organic-chemical questions to retrieve information for problem-solving and communication to others.

Regarding judgement and approach:
 

• describe procedures and suggest applications of modern drug design, and reflect on it in the context of drug development by the pharmaceutical industry.

The course content is oriented towards substances and methods of special biomedical interest and provides a basis for later courses in the programme.

The course is divided into the following 6 parts:

Laboratory techniques with laboratory safety. Common methods in organic-chemical and bioorganic synthesis work. Classification and labeling of chemicals, standard values and limits. Lab reports.

The teaching includes lectures, laboratory sessions, group tuition (seminars), study visits and project work. It is, to a large extent, directed towards problem-solving. The project work is an advanced study in groups, with an emphasis on integration of own work and literature studies.

Part 1. Basic chemistry (2 credits). The examination consists of a written test. Graded Fail/Pass.

Part 2. Carbonyl and unsaturated compounds (3 credits). The examination consists of a written test. Graded Fail/Pass.

Part 3. Organic and bioorganic chemistry, incl. project work (2 credits). The examination consists of an oral presentation of the project work. Graded Fail/Pass. A written test with voluntary participation will be offered. The results of this test may be beneficial for grading of the course (bonus points). 

Part 4. Environmental and medicinal chemistry (1 credit). The examination consists of a poster presentation about the study visit. Graded Fail/Pass.

Part 5. Organic-chemical laboratory work (6 credits). The examination consists of a written test in laboratory safety and techniques, observations of the student's laboratory skills, and labreports. Graded Fail/Pass. The results of lab reports may be beneficial for the grading of the course (bonus points).

Part 6. Integration of theory and practice (6 credits). The examination consists of a written exami covering te entire content of the course. Graded Fail/Pass/Pass with distinction. For participation in the written examination it is required that the part 1 (Basic chemistry) and part 2 (Carbonyl and unsaturated compounds) are passed. To pass the whole course the grade of pass must have been obtained for all parts of the course. The final grade for the whole course is based on the grade for the part 6 (Integration of theory and practice) and the collected bonus points.

Compulsory participation
Laboratory sessions, project work, and study visit are compulsory, as well as presentations and lectures linked to these parts. Part of the course is an examination in laboratory safety and technology that must be passed before start of the subsequent laboratory sessions. At the beginning of each laboratory session, an oral examination is performed that must be approved before the student starts experimenting. The course director assesses if and, in that case, how absence can be compensated. Before the student has participated in all compulsory parts or compensated absence in accordance with the course director's instructions, the student's results for respective part will not be registered in LADOK.

Limited number of examinations or practical training sessions
Students who have not passed the first examination are entitled to participate in five more examinations. If the student has not passed the exam after four attempts he/she is encouraged to contact the study advisor.  If the student has failed six examinations, no additional examination or new admission is provieded.

The number of times that the student has participated in one and the same examination is regarded as an examination session. Submission of a blank examination is regarded as an examination. An examination, for which the student registered but not participated in, will not be counted as an examination.

The course is cancelled and was offered for the last time HT16. Examination according to this syllabus will be offered for the last time VT21 for students who have not completed the course with a passing grade.

The course language is English.

Course evaluation will be carried out in accordance with the guidelines established by the Board of Higher Education.

Oral evaluation in the form of course council meetings will be carried out during the course.