Course syllabus for

Risk Assessment and In Silico Toxicology, 10 credits

Riskbedömning och in silico-toxikologi, 10 hp
This course syllabus is valid from autumn 2019.
Please note that the course syllabus is available in the following versions:
Autumn2019 , Autumn2020
Course code
Course name
Risk Assessment and In Silico Toxicology
10 credits
Form of Education
Higher Education, study regulation 2007
Main field of study 
AV - Second cycle 
Grading scale
Fail (U) or pass (G)
Institute of Environmental Medicine
Decided by
Education committee IMM
Decision date
Course syllabus valid from
Autumn 2019

Specific entry requirements

At least the grade pass on all courses within the first year of the Master's Programme in Toxicology.


Upon completion of the course, the student should be able to:

Regarding knowledge and understanding

  • explain recent advances within research and development in risk assessment and in silico toxicology,

Regarding skills and ability

  • analyse and discuss relevant literature,
  • apply an appropriate method to assess the reliability of scientific studies,
  • choose and use appropriate statistical methods for analysis of results from toxicity studies,

Regarding judgement and approach

  • demonstrate ability to make scientific assessment by analysis and discussion of scientific literature and/or seminars.


The course is divided into the following parts:

Biostatistics, 2.5 hp

Grading scale: GU

Advanced statistical methods for the analysis of repeated observations, nonlinear dose-response curve estimation, survival data, outcome transformations, and missing data.

Risk assessment and in silico toxicology, 7.5 hp

Grading scale: GU

Recent advances within research and development in health risk assessment and toxicology. Methods for the assessment of reliability of studies in the area of toxicological research.

Teaching methods

The course is an advanced course and it is assumed that students take responsibility to acquire knowledge. Teaching will be in the form of lectures, seminars, assignments, journal clubs, workshops and computer exercises.


Biostatistics (2.5 credits). The examination consists of a written examination. Graded Pass/Fail.
Risk assessment and in silico toxicology (7.5 credits). The examination consists of oral and/or written assignments. Graded Pass/Fail.
For the grade Pass in the course a Pass is required for both parts.

If there are special grounds, or a need for adaptation for a student with a disability, the examiner may decide to deviate from the syllabus's regulations on the examination form, the number of examination opportunities, the possibility of supplementation or exemptions from the compulsory section/s of the course etc. Content and learning outcomes as well as the level of expected skills, knowledge and abilities may not be changed, removed or reduced.
Compulsory participation:
Attendance at the seminars, journal clubs and workshops. The course director assesses if and, in that case, how absence can be compensated. Before the student has participated in all compulsory parts or compensated absence in accordance with the course director's instructions, the student's results will not be registered in LADOK.

Transitional provisions

After each course occasion there will be at least six occasions for the examination within a two-year period from the end of the course.

Other directives

The course is given in English.

Course evaluation will be carried out in accordance with the guidelines established by the Board of Higher Education.

Oral evaluation in the form of course council meetings will be carried out during the course.

Literature and other teaching aids


Course literature is scientific papers and material handout out during the course.