Risk Assessment and In Silico Toxicology, 8.5 credits

At least the grade pass on all courses within the first year of the Master's Programme in Toxicology.

Upon completion of the course, the student should be able to:

Regarding knowledge and understanding

• explain recent advances within research and development in risk assessment and in silico toxicology,

Regarding skills and ability

• analyse and discuss relevant literature,
• apply an appropriate method to assess the reliability of scientific studies,
• choose and use appropriate statistical methods for analysis of results from toxicity studies,

Regarding judgement and approach

• demonstrate ability to make scientific assessment by analysis and discussion of scientific literature and/or seminars.

The course is divided into the following parts:

Advanced statistical methods for the analysis of repeated observations, nonlinear dose-response curve estimation, survival data, outcome transformations, and missing data.

Recent advances within research and development in health risk assessment and toxicology. Methods for the assessment of reliability of studies in toxicology.

The course is an advanced course and it is assumed that students take responsibility to acquire knowledge. Teaching will be in the form of lectures, seminars, assignments, journal clubs, workshops and computer exercises.

Biostatistics (2.5 credits). The examination consists of a written examination. Graded Pass/Fail.
 
Risk assessment and in silico toxicology (6 credits). The examination consists of oral and/or written assignments. Graded Pass/Fail.
 
For the grade Pass in the course a Pass is required for both parts.

If there are special grounds, or a need for adaptation for a student with a disability, the examiner may decide to deviate from the syllabus's regulations on the examination form, the number of examination opportunities, the possibility of supplementation or exemptions from the compulsory section/s of the course etc. Content and learning outcomes as well as the level of expected skills, knowledge and abilities may not be changed, removed or reduced.
 
Compulsory participation:
Attendance at the seminars, journal clubs and workshops.  The examiner assesses if, and in that case how, absence can be compensated. Before the student has participated in all compulsory parts or compensated absence in accordance with the examiner's instructions, the student's results for respective part will not be registered. Absence from a compulsory activity may result in that the student cannot compensate the absence until the next time the course is given.

The course is given in English.