For students attending the course Applications of Methods in Toxicological Research (16.5 credits) course code 4TX030

Content

This course is divided into the following four parts:

Practical laboratory methods in toxicology, 7.5 hp

This part contains the theory and practical application of current laboratory research methods in toxicology, including alternative methods such as in vitro and alternative animal models.

In addition, the theory and practical application of basic principles and methods of omics and bioinformatic analyses in toxicology research.

Laboratory technology and laboratory safety are included. The methods included may vary from course to course depending on current research topics. Examples of methods that may be included are: molecular biology methods for the analysis of DNA, RNA levels, protein levels, and enzyme activity. Methods for determination of DNA-damage and cellular toxicity. 

This part also contains scientific writing. 

Alternative methods for toxicity testing, 1.5 hp

This part contains analysis of need, development, validation and regulatory acceptance of alternative methods (according to 3R) for toxicological testing.

Biostatistics, 1.5 hp

This part contains the theory and practical application of basic statistical principles and methods that are applied in experimental toxicological research.

Integration of methods in toxicological research, 6.0 hp

The course is completed with an integrating part where the contents from Practical laboratory methods in toxicology and Alternative methods for toxicological testing are examined.

Teaching methods
The teaching includes laboratory sessions (including computer exercises), lectures/seminars, written reports and oral presentations.

Schedule

The schedule for the spring semester 2025 will be published 2 weeks before the start of the course.

Examination and compulsory participation

Practical laboratory methods in toxicology (7.5 credits). The examination consists of individual written laboratory reports. Graded Fail/Pass/Pass with distinction.

Alternative methods for toxicological testing (1.5 credits). The examination consists of individual written reports and oral presentations. Graded Fail/Pass.

Integration of methods in toxicological research (6.0 credits). The examination consists of written examination. Graded Fail/Pass/Pass with distinction.

Biostatistics (1.5 credits). The examination consists of written examination. Graded Fail/Pass.
 
To get pass with distinction as the final grade of the course pass with distinction is required for both parts: Practical laboratory methods in toxicology and Integration of methods in toxicological research. To pass the whole course the grade pass must have been obtained for all parts of the course.

Compulsory participation
All practical modules including presentations and occasional lectures (indicated in the schedule) are compulsory.
The course director assesses if, and in that case how, absence can be compensated. Before the student has participated in all compulsory parts or compensated absence in accordance with the course director's instructions, the student's results for respective part will not be registered . Absence from a compulsory activity may result in that the student cannot compensate the absence until the next time the course is given.

Course evaluation 

Course evaluation will be carried out in accordance with the guidelines established by the Board of Education. Course council meeting is held with the course coordinator and student representatives.

Contact